In high-density urban environments, buildings with mixed- use programs increasingly include public and common spaces on elevated levels. The complex interactions of such spaces with those on the ground level, their impact on patterns of human movement in the city, and their scalability and potential contribution to providing a more livable high- density urban environment are currently not well understood. This paper presents an ongoing research project at the Singapore University of Technology and Design (SUTD) that uses a Complexity Science-based approach to quantitatively analyze the network effects of vertically integrated mixed-use urban developments on human movement and space use. The research uses Kampung Admiralty, a first-of-its-kind development in Singapore that integrates housing for the elderly with a wide range of social healthcare, communal, commercial, and retail facilities, as a case study. The paper finally discusses the potential of the research approach to inform future urban planning and design of vertically integrated mixed-use developments.